Description

2C-Hydroxymethyl-2,3:5,6-Di-o-Isopropylidene-D-Mannono-1,4-Lactone is a high-purity, protected sugar lactone derivative that serves as a critical chiral building block and advanced intermediate in sophisticated organic synthesis. Its value lies in its ability to introduce complex stereochemistry and functional groups, enabling the production of high-value fine chemicals and active pharmaceutical ingredients (APIs). This compound is essential for research and manufacturing chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable access to high-quality, stereochemically defined intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of nucleoside analogs, antiviral agents, and other complex therapeutic molecules.
• Agrochemical Synthesis: Used in the research and development of novel, stereoselective pesticides and herbicides.
• Carbohydrate Chemistry Research: Serves as a protected precursor for the synthesis of complex oligosaccharides, glycoconjugates, and glycomimetics.
• Fine Chemical Production: Employed as a building block for flavors, fragrances, and other specialty chemicals requiring specific stereochemistry.
• Academic & R&D Laboratories: A valuable tool for methodological development in asymmetric synthesis and total synthesis projects.

Basic Information

Product Name	2C-Hydroxymethyl-2,3:5,6-Di-o-Isopropylidene-D-Mannono-1,4-Lactone
CAS No.	70147-48-7
Molecular Formula	C13H20O7
Molecular Weight	288.29 g/mol
Synonyms	2-C-Hydroxymethyl-2,3:5,6-di-O-isopropylidene-D-mannono-1,4-lactone; 2-C-(Hydroxymethyl)-2,3:5,6-di-O-isopropylidene-D-mannono-1,4-lactone; D-Mannono-1,4-lactone, 2-C-(hydroxymethyl)-2,3:5,6-di-O-(1-methylethylidene)-; Isopropylidene-D-mannono-lactone derivative; Protected D-mannonolactone; Chiral sugar lactone intermediate.
EINECS	Contact for details

Quality Control

Our 2C-Hydroxymethyl-2,3:5,6-Di-o-Isopropylidene-D-Mannono-1,4-Lactone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided to guarantee consistent quality, identity, and purity for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.