Description

Benzoyl Fluoride, 2-(Difluoromethyl)- (9Ci) is a specialized fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound is valued for its unique reactivity profile, where the benzoyl fluoride moiety and the difluoromethyl group offer distinct handles for selective functionalization. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the construction of complex molecules, particularly those requiring the incorporation of fluorine atoms to modulate biological activity, metabolic stability, and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), especially in protease inhibitor and kinase inhibitor research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides where the difluoromethyl group enhances lipophilicity and systemic activity.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers with tailored surface properties and chemical resistance.
• Fluorine Chemistry Research: An essential reagent for studying new fluorination methodologies and C-F bond formation reactions in academic and industrial laboratories.
• Liquid Crystal & OLED Materials: Employed in the synthesis of fluorinated organic semiconductors and liquid crystal compounds for electronic displays.

Basic Information

Product Name	Benzoyl Fluoride, 2-(Difluoromethyl)- (9Ci)
CAS No.	70093-44-6
Molecular Formula	C8H5F3O
Molecular Weight	174.12 g/mol
Synonyms	2-(Difluoromethyl)benzoyl Fluoride; α,α-Difluoro-o-toluoyl Fluoride; o-(Difluoromethyl)benzoyl Fluoride; Benzoyl fluoride, 2-(difluoromethyl)-; 2-Difluoromethylbenzoyl fluoride
EINECS	Contact for details

Quality Control

Every batch of Benzoyl Fluoride, 2-(Difluoromethyl)- (9Ci) is manufactured and analyzed under strict quality management protocols. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We support custom synthesis and can tailor specifications to meet specific project requirements, including research-grade to GMP-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and highly volatile nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) at temperatures between 2°C and 8°C for long-term stability. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.