Description

1-Chloro-4-Prop-2-Ynyl-Benzene is a versatile aromatic alkyne intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a key building block in the construction of complex molecular architectures, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries for applications such as cross-coupling reactions and the synthesis of bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, particularly those requiring a halogenated aryl alkyne moiety.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides, where its structural motif can contribute to biological activity.
• Material Science & Polymer Chemistry: Acts as a monomer or cross-linking agent in the development of specialty polymers, resins, and advanced materials with tailored properties.
• Organic Synthesis & Catalysis: A valuable substrate in Sonogashira, Heck, and other palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Ligand & Catalyst Development: Employed in the preparation of novel ligands and organometallic complexes for catalytic applications.
• Life Sciences Research: Utilized as a biochemical probe or a tagging reagent in chemical biology and medicinal chemistry research programs.

Basic Information

Product Name	1-Chloro-4-Prop-2-Ynyl-Benzene
CAS No.	70090-69-6
Molecular Formula	C9H7Cl
Molecular Weight	150.60 g/mol
Synonyms	1-Chloro-4-(prop-2-yn-1-yl)benzene; 4-Chlorophenylacetylene; p-Chlorophenylacetylene; (4-Chlorophenyl)ethyne; 1-Chloro-4-ethynylbenzene; 4-Ethynylchlorobenzene; 70090-69-6; p-Ethynylchlorobenzene
EINECS	Contact for details

Quality Control

Our 1-Chloro-4-Prop-2-Ynyl-Benzene is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. Due to its light-sensitive nature, containers should be amber or otherwise opaque.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.