Description

(R)-(+)-1,2,4-Butanetriol CAS NO 70005-88-8 is a high-purity, chiral triol building block of significant importance in asymmetric synthesis and pharmaceutical development. Its value lies in its defined stereochemistry, which is crucial for creating enantiomerically pure compounds with specific biological activities. This product is essential for research chemists and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require a reliable source of a key chiral intermediate.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly for antiviral and cardiovascular drugs.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides where specific stereochemistry is required for efficacy and environmental safety.
• Ligand and Catalyst Development: Serves as a backbone for synthesizing chiral ligands and organocatalysts used in asymmetric catalysis.
• Polymer Chemistry: Employed as a monomer or cross-linking agent for producing specialty polymers with tailored properties, such as polyesters and polyurethanes.
• Fine Chemical Synthesis: A versatile building block for synthesizing complex natural products, flavors, and fragrances.
• Bioconjugation and Linker Chemistry: Its three hydroxyl groups make it useful for creating spacers and linkers in bioconjugation applications and prodrug design.

Basic Information

Product Name	(R)-(+)-1,2,4-Butanetriol
CAS No.	70005-88-8
Molecular Formula	C4H10O3
Molecular Weight	106.12 g/mol
Synonyms	(R)-1,2,4-Trihydroxybutane; (R)-(+)-1,2,4-Trihydroxybutane; D-1,2,4-Butanetriol; (R)-Butane-1,2,4-triol; (2R)-1,2,4-Butanetriol; (R)-1,2,4-BT; (R)-BT; (R)-THB; (R)-1,2,4-THB
EINECS	Contact for details

Quality Control

Our (R)-(+)-1,2,4-Butanetriol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and specific impurities are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Specific Rotation [α]	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.