Description

1,1,3-Triethoxypropane is a versatile acetal compound with a high degree of reactivity, making it a valuable building block in organic synthesis. Its primary value lies in its role as a protected form of malondialdehyde, a key intermediate for heterocyclic chemistry and cross-coupling reactions. This chemical is essential for research and development laboratories, pharmaceutical synthesis, and manufacturers of specialty chemicals and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those containing pyrimidine and other nitrogen-containing heterocycles.
• Organic Synthesis Building Block: Used as a protected 1,3-dicarbonyl synthon for the preparation of complex molecules via aldol, Michael addition, and cyclization reactions.
• Cross-Coupling Reactions: Serves as a substrate in palladium-catalyzed reactions for creating carbon-carbon bonds in advanced material and fine chemical production.
• Flavor and Fragrance Industry: Employed in the synthesis of aroma chemicals and flavoring agents due to its ability to form specific aldehydes upon hydrolysis.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the development of specialty polymers and resins with tailored properties.
• Research & Development: A standard reagent in academic and industrial R&D for exploring new synthetic methodologies and creating novel chemical entities.

Basic Information

Product Name	1,1,3-Triethoxypropane
CAS No.	7789-92-6
Molecular Formula	C9H20O3
Molecular Weight	176.25 g/mol
Synonyms	Malondialdehyde bis(diethyl acetal); 1,1,3-Triethoxypropane; Propane, 1,1,3-triethoxy-; Malonaldehyde bis(diethyl acetal); Diethyl malondialdehyde bis(acetal); Malondialdehyde diethyl acetal; 3,3-Diethoxypropionaldehyde diethyl acetal; Acetaldehyde, (3,3-diethoxypropylidene)diethyl acetal
EINECS	232-161-1

Quality Control

Our 1,1,3-Triethoxypropane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment ensures the material is suitable for demanding applications in pharmaceutical and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature is 2-8°C for extended stability, though short-term storage at 15-25°C is acceptable.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20/D)	1.408 - 1.412
Density (20°C)	0.92 - 0.96 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.