Description

3-Chloro-2-Methylpropionitrile is a versatile halogenated nitrile intermediate with significant synthetic utility. Its reactive chloro and nitrile functional groups make it a valuable building block for constructing more complex molecules in fine chemical and pharmaceutical synthesis. This compound is primarily sought by research and development chemists and process engineers in the agrochemical, pharmaceutical, and specialty chemical industries for applications ranging from active ingredient development to polymer modification.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those containing cyanoalkyl or chlorinated moieties.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where its structure serves as a core for building bioactive molecules.
• Organic Synthesis Building Block: Employed in nucleophilic substitution and cyano-group transformation reactions to introduce functionalized propionitrile chains.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the production of specialty polymers and resins.
• Chemical Research: Serves as a standard or starting material in methodological development and scale-up studies within R&D laboratories.

Basic Information

Product Name	3-Chloro-2-Methylpropionitrile
CAS No.	7659-45-2
Molecular Formula	C4H6ClN
Molecular Weight	103.55 g/mol
Synonyms	2-Methyl-3-chloropropionitrile; β-Chloroisobutyronitrile; 3-Chloro-2-methylpropanenitrile; (2-Methyl-3-chloropropyl) cyanide; Isobutyronitrile, 3-chloro-; NSC 9375; 3-Chloroisobutyronitrile
EINECS	231-619-0

Quality Control

Our 3-Chloro-2-Methylpropionitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including assay by GC/HPLC, identity confirmation (IR, NMR), and impurity profiling to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) documenting purity, physical properties, and safety data are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. The container must be kept tightly sealed due to potential sensitivity to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.435 - 1.445
Density (20°C)	1.05 - 1.10 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.