Description

Alpha,α-Dibromo-4-Fluoroacetophenone is a specialized halogenated aromatic ketone, serving as a versatile and critical building block in advanced organic synthesis. Its unique dibromoacetyl moiety adjacent to a fluoro-substituted phenyl ring makes it a highly reactive electrophile, essential for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the fluorine atom enhances biological activity and environmental stability.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials.
• Chemical Biology Probes: Employed in the creation of activity-based probes (ABPs) for studying enzyme mechanisms and protein functions.
• Custom Synthesis & Contract Manufacturing: A fundamental reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	Alpha,α-Dibromo-4-Fluoroacetophenone
CAS No.	7542-64-5
Molecular Formula	C8H5Br2FO
Molecular Weight	295.93 g/mol
Synonyms	4'-Fluoro-α,α-dibromoacetophenone; 2,2-Dibromo-1-(4-fluorophenyl)ethanone; 1-(4-Fluorophenyl)-2,2-dibromoethanone; p-Fluoro-α,α-dibromoacetophenone; Dibromo(4-fluorophenyl)methanone; NSC 404087; α,α-Dibromo-p-fluoroacetophenone
EINECS	Contact for details

Quality Control

Our Alpha,α-Dibromo-4-Fluoroacetophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical parameters. Our quality commitment ensures batch-to-batch consistency, supply reliability, and compliance with global regulatory expectations for chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging. Store separately from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	88 - 92 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.