Description

2,3,5,6-Tetramethylbenzyl Chloride is a versatile and highly functionalized organic intermediate characterized by its chloromethyl group attached to a heavily substituted benzene ring. This compound is valued for its role as a key building block in the synthesis of more complex molecules, enabling the introduction of the benzyl moiety into target structures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients, ligands, and advanced materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for constructing complex molecular architectures.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators where the tetramethylbenzyl group imparts specific biological activity.
• Ligand and Catalyst Preparation: Employed in organometallic chemistry to create specialized ligands for catalytic systems and metal-organic frameworks (MOFs).
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of advanced colorants and optical materials.
• Polymer Modification: Utilized to introduce functional groups into polymer chains, altering physical properties for specialty plastic and resin applications.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D for exploring new chemical reactions and pathways.

Basic Information

Product Name	2,3,5,6-Tetramethylbenzyl Chloride
CAS No.	7435-83-8
Molecular Formula	C11H15Cl
Molecular Weight	182.69 g/mol
Synonyms	(2,3,5,6-Tetramethylphenyl)methyl Chloride; 1-(Chloromethyl)-2,3,5,6-tetramethylbenzene; 2,3,5,6-Tetramethylbenzyl Chloride; α-Chloro-2,3,5,6-tetramethyltoluene; Pentamethylbenzyl Chloride (common misnomer); TMB-Cl; TMBC
EINECS	Contact for details

Quality Control

Our 2,3,5,6-Tetramethylbenzyl Chloride is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing to ensure high purity, identity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality systems are designed to meet the stringent requirements of GMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.