Description

2,4-Dichloro-5-Methylsulfanylpyrimidine is a versatile halogenated pyrimidine derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional reactivity, featuring both chloro and methylthio substituents, makes it a valuable precursor for constructing complex heterocyclic systems. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of antiviral, anticancer, and kinase inhibitor drug candidates.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and other crop protection chemicals.
• Material Science Research: Serves as a monomer or precursor for functional polymers and liquid crystals.
• Chemical Biology: Employed in the development of molecular probes and enzyme inhibitors for biochemical research.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs for bespoke chemical development.
• Academic Research: Used in university and institutional labs for methodological development and heterocyclic chemistry studies.

Basic Information

Product Name	2,4-Dichloro-5-Methylsulfanylpyrimidine
CAS No.	7401-98-1
Molecular Formula	C5H4Cl2N2S
Molecular Weight	195.07 g/mol
Synonyms	5-(Methylthio)-2,4-dichloropyrimidine; 2,4-Dichloro-5-(methylthio)pyrimidine; 2,4-Dichloro-5-methylmercaptopyrimidine; 5-Methylsulfanyl-2,4-dichloropyrimidine; 2,4-Dichloro-5-(methylsulfanyl)pyrimidine; 2,4-Dichloro-5-methylthiopyrimidine; 7401-98-1; Pyrimidine, 2,4-dichloro-5-(methylthio)-
EINECS	Contact for details

Quality Control

Our 2,4-Dichloro-5-Methylsulfanylpyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, purity, and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be amber-colored or stored in a dark place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.