Description

2-Chloro-2,5-Dichloroacetophenone is a versatile chlorinated aromatic ketone intermediate of significant importance in advanced organic synthesis. Its unique halogenated structure makes it a valuable building block for the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for research and production chemists seeking to introduce specific chlorinated acetophenone motifs into target compounds, enabling the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring a halogenated acetophenone core structure.
• Agrochemical Synthesis: Used in the research and development of herbicides, fungicides, and pesticides, where its chlorinated pattern can enhance biological activity.
• Organic Synthesis Building Block: Serves as a versatile electrophile in Friedel-Crafts acylation and nucleophilic substitution reactions for constructing complex aromatic ketones.
• Material Science Research: Investigated as a monomer or cross-linking agent in the development of specialty polymers with specific thermal or chemical resistance properties.
• Dye and Pigment Intermediate: Employed in the synthesis of specialized dyes and organic pigments, leveraging its aromatic ketone functionality.

Basic Information

Product Name	2-Chloro-2,5-Dichloroacetophenone
CAS No.	7396-79-4
Molecular Formula	C8H5Cl3O
Molecular Weight	223.48 g/mol
Synonyms	2,2',5'-Trichloroacetophenone; 1-(2,5-Dichlorophenyl)-2-chloroethanone; α,2,5-Trichloroacetophenone; 2-Chloro-1-(2,5-dichlorophenyl)ethanone; NSC 403796; 2,5-Dichloro-ω-chloroacetophenone; ω,2,5-Trichloroacetophenone
EINECS	Contact for details

Quality Control

Our 2-Chloro-2,5-Dichloroacetophenone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation. A Certificate of Analysis (COA) detailing all relevant specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases, reducing agents, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.