Description

2-Chloro-4-Methylbenzonitrile is a versatile halogenated aromatic nitrile building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both a chloro and a methyl substituent on the benzonitrile core, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with aryl-nitrile functionalities.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where the chloro and nitrile groups are essential for biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and advanced polymers.
• Dye and Pigment Intermediate: Acts as a building block for synthesizing complex colorants and functional dyes.
• Custom Synthesis and R&D: A valuable reagent for contract research organizations and academic labs exploring novel heterocyclic compounds.

Basic Information

Product Name	2-Chloro-4-Methylbenzonitrile
CAS No.	7390-42-3
Molecular Formula	C8H6ClN
Molecular Weight	151.59 g/mol
Synonyms	2-Chloro-p-tolunitrile; 4-Methyl-2-chlorobenzonitrile; 2-Chloro-4-methylbenzenecarbonitrile; 2-Chloro-4-tolunitrile; 2-Chloro-4-cyanotoluene; Benzonitrile, 2-chloro-4-methyl-; 2-Chloro-4-methyl-benzonitril
EINECS	230-987-7

Quality Control

Our 2-Chloro-4-Methylbenzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	65 - 68 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.