Description

p-Azidophenyl Sulfone is a specialized aromatic sulfone derivative featuring a reactive azido functional group. This compound is a critical photoactive cross-linking agent and chemical intermediate valued for its ability to undergo photolysis or thermal decomposition to generate highly reactive nitrene species. It is essential for researchers and manufacturers in advanced material science and life sciences who require precise molecular conjugation and surface modification capabilities.

Application

• Photoaffinity Labeling Probes: Used in biochemical research to study protein-ligand interactions and binding sites through covalent cross-linking upon UV irradiation.
• Polymer & Material Cross-Linking: Serves as a photoinitiator and cross-linker in the synthesis of specialty polymers, hydrogels, and photoresists to enhance material properties.
• Surface Functionalization: Employed to modify surfaces (e.g., glass, gold, polymers) with azido groups for subsequent "click chemistry" reactions, such as with alkynes via CuAAC.
• Bioconjugation Reagent: Facilitates the covalent attachment of biomolecules (proteins, oligonucleotides) to other molecules, particles, or solid supports under mild conditions.
• Pharmaceutical Intermediate: Acts as a key building block in the synthesis of more complex molecules for drug discovery and development programs.
• Advanced Composite Materials: Incorporated into epoxy resins and other matrix materials to create high-performance composites with tailored thermal and mechanical stability.

Basic Information

Product Name	p-Azidophenyl Sulfone
CAS No.	7300-27-8
Molecular Formula	C12H8N4O2S
Molecular Weight	272.28 g/mol
Synonyms	4-Azidophenyl Sulfone; 4,4'-Sulfonylbis(azidobenzene); Bis(4-azidophenyl) Sulfone; p,p'-Sulfonylbis(azidobenzene); 1-Azido-4-[(4-azidophenyl)sulfonyl]benzene; Azidosulfone; Photoactive Sulfone Crosslinker; CAS 7300-27-8
EINECS	Contact for details

Quality Control

Our p-Azidophenyl Sulfone is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and industrial applications. Each lot is analyzed using advanced techniques including HPLC, NMR, and FT-IR to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles where applicable to support our customers' quality management systems.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and the presence of the azido group, prolonged exposure to direct light or heat sources should be avoided. Keep away from incompatible materials such as strong reducing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.