Description

3-Fluoro-1-O,2-O,4-O,6-o-Tetraacetyl-3-Deoxy-β-D-Glucopyranose is a key fluorinated carbohydrate derivative, serving as a crucial synthetic intermediate in advanced organic and medicinal chemistry. Its value lies in providing a protected, reactive scaffold for the selective introduction of fluorine into complex molecular architectures, enabling the development of novel bioactive compounds. This high-purity building block is essential for researchers and manufacturers in pharmaceutical development, agrochemical synthesis, and advanced material science.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated nucleoside analogs, antiviral agents, and other bioactive molecules where fluorine substitution modulates potency, metabolic stability, and bioavailability.
• Glycochemistry Research: Used as a specialized building block for constructing fluorinated sugars and complex oligosaccharides to study enzyme mechanisms, develop glycosidase inhibitors, and create molecular probes.
• Agrochemical Synthesis: Employed in the development of new-generation fluorinated pesticides and herbicides, where the fluorine atom can enhance biological activity and environmental persistence.
• Diagnostic Probe Development: Serves as a starting material for synthesizing 18F-labeled PET (Positron Emission Tomography) tracers and other imaging agents used in medical diagnostics.
• Material Science: Potential use in creating fluorinated surfactants, liquid crystals, or specialty polymers with unique surface properties and stability.

Basic Information

Product Name	3-Fluoro-1-O,2-O,4-O,6-o-Tetraacetyl-3-Deoxy-β-D-Glucopyranose
CAS No.	7226-43-9
Molecular Formula	C14H19FO9
Molecular Weight	350.29 g/mol
Synonyms	3-Deoxy-3-fluoro-1,2,4,6-tetra-O-acetyl-β-D-glucopyranose; 3-Fluoro-1,2,4,6-tetra-O-acetyl-3-deoxy-β-D-glucopyranose; 3-Fluoro-3-deoxy-1,2,4,6-tetra-O-acetyl-β-D-glucopyranose; β-D-Glucopyranose, 3-deoxy-3-fluoro-, 1,2,4,6-tetraacetate; Tetraacetyl-3-fluoro-3-deoxy-β-D-glucopyranose
EINECS	Contact for details

Quality Control

Our 3-Fluoro-1-O,2-O,4-O,6-o-Tetraacetyl-3-Deoxy-β-D-Glucopyranose is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and specific tests for residual solvents and moisture, to ensure it meets the exacting standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and reactivity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.