Description

1-Benzhydryl-1H-Imidazole is a versatile nitrogen-containing heterocyclic compound that serves as a crucial intermediate in advanced organic synthesis. Its unique benzhydryl-substituted imidazole structure makes it a valuable building block for developing pharmaceuticals and specialty chemicals. This high-purity compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and material science industries seeking to create novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the development of novel fungicides, herbicides, and plant growth regulators due to its bioactive imidazole core.
• Ligand and Catalyst Preparation: Serves as a precursor for N-heterocyclic carbene (NHC) ligands and other organocatalysts used in asymmetric synthesis and polymerization reactions.
• Material Science Research: Building block for creating advanced polymers, ionic liquids, and metal-organic frameworks (MOFs) with tailored properties.
• Chemical Biology Probes: Utilized in medicinal chemistry for constructing molecular probes and inhibitors to study enzyme function and biological pathways.
• Custom Synthesis: Foundation for contract research organizations (CROs) and custom synthesis houses to produce client-specific novel chemical entities (NCEs).

Basic Information

Product Name	1-Benzhydryl-1H-Imidazole
CAS No.	7189-67-5
Molecular Formula	C₁₆H₁₄N₂
Molecular Weight	234.30 g/mol
Synonyms	1-(Diphenylmethyl)-1H-imidazole; 1-(Diphenylmethyl)imidazole; Benzhydrylimidazole; NSC 163049; Diphenylmethylimidazole; 1H-Imidazole, 1-(diphenylmethyl)-; Imidazole, 1-(diphenylmethyl)-
EINECS	Contact for details

Quality Control

Our 1-Benzhydryl-1H-Imidazole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as identity, assay, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, and we support our clients' regulatory submissions with full traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.