Description

1-Iodo-2,4,5-Trichlorobenzene is a halogenated aromatic compound of significant interest in advanced organic synthesis. This versatile building block is valued for its unique reactivity, where the iodine atom serves as an excellent leaving group in metal-catalyzed cross-coupling reactions. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a specific halogenated benzene core.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides where the trichloro-iodo substitution pattern imparts specific biological activity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and liquid crystals.
• Cross-Coupling Reactions: An essential substrate for Suzuki, Stille, and Negishi couplings to form biaryl and other carbon-carbon bonds.
• Chemical Reference Standard: Utilized in analytical laboratories for method development and calibration in chromatographic systems.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for exploring novel reaction pathways and synthesizing complex organic molecules.

Basic Information

Product Name	1-Iodo-2,4,5-Trichlorobenzene
CAS No.	7145-82-6
Molecular Formula	C6H2Cl3I
Molecular Weight	323.34 g/mol
Synonyms	2,4,5-Trichloro-1-iodobenzene; 2,4,5-Trichloroiodobenzene; 1-Iodo-2,4,5-trichlorobenzol; Benzene, 1-iodo-2,4,5-trichloro-; NSC 92446
EINECS	Contact for details

Quality Control

Our 1-Iodo-2,4,5-Trichlorobenzene is manufactured under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and industry standards for research and process chemistry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.