Description

Cyclopentanone, 2-(2,2,2-Trifluoro-1-Hydroxyethylidene)- (8Ci,9Ci) CAS NO 7130-27-0 is a specialized fluorinated ketone derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring a trifluoromethylated hydroxyethylidene moiety fused to a cyclopentanone ring, makes it a valuable precursor for synthesizing complex molecules with tailored properties. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors seeking to incorporate fluorine atoms to modulate bioactivity, metabolic stability, and lipophilicity.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the introduction of fluorine enhances environmental stability and biological activity.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers, coatings, and liquid crystals with unique thermal and chemical resistance properties.
• Organic Synthesis & Catalysis: A versatile reagent in organofluorine chemistry for constructing complex carbon skeletons and as a ligand precursor in catalytic systems.
• Fine Chemical Production: Employed in the manufacture of dyes, flavors, and fragrances requiring specific fluorinated structural motifs.

Basic Information

Product Name	Cyclopentanone, 2-(2,2,2-Trifluoro-1-Hydroxyethylidene)- (8Ci,9Ci)
CAS No.	7130-27-0
Molecular Formula	C7H7F3O2
Molecular Weight	180.12 g/mol
Synonyms	2-(2,2,2-Trifluoro-1-hydroxyethylidene)cyclopentanone; 2-(Trifluoroacetyl)cyclopentanone enol; 1-Hydroxy-2,2,2-trifluoroethylidenecyclopentanone; 2-(1-Hydroxy-2,2,2-trifluoroethylidene)cyclopentanone; 2-(2,2,2-Trifluoro-1-hydroxyethylidene)cyclopentan-1-one; Trifluoromethyl hydroxyethylidene cyclopentanone; TFHCP; (8CI,9CI) designation compound
EINECS	Contact for details

Quality Control

Every batch of Cyclopentanone, 2-(2,2,2-Trifluoro-1-Hydroxyethylidene)- is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy to ensure identity, purity, and consistency meet the stringent requirements of our global clientele. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment, supporting regulatory filings and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as oxidizing agents. The container must be kept tightly sealed to prevent moisture absorption and potential decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.