Description

1-Bromo-2-(tert-Butyl)Benzene is a high-purity, substituted aromatic bromide serving as a versatile and critical building block in advanced organic synthesis. Its value lies in the strategic positioning of the bulky tert-butyl group ortho to the reactive bromine atom, which directs subsequent metal-catalyzed cross-couplings and functional group transformations with high regioselectivity. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty materials industries developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those requiring sterically hindered biaryl structures via Suzuki-Miyaura or Buchwald-Hartwig coupling reactions.
• Agrochemical Synthesis: Used in constructing advanced herbicides, fungicides, and insecticides where the tert-butyl moiety enhances lipophilicity and biological activity.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing specialized phosphine and N-heterocyclic carbene (NHC) ligands used in asymmetric catalysis.
• Material Science Research: Employed in the creation of organic semiconductors, liquid crystals, and polymers with tailored electronic and steric properties.
• Chemical Reference Standard: Used for analytical method development, calibration, and quality control in chemical manufacturing.

Basic Information

Product Name	1-Bromo-2-(tert-Butyl)Benzene
CAS No.	7073-99-6
Molecular Formula	C10H13Br
Molecular Weight	213.12 g/mol
Synonyms	2-Bromo-1-tert-butylbenzene; 2-tert-Butylbromobenzene; 1-tert-Butyl-2-bromobenzene; o-tert-Butylbromobenzene; 2-(tert-Butyl)phenyl bromide; (2-Bromophenyl)-tert-butane; 7073-99-6; tert-Butyl-2-bromobenzene
EINECS	Contact for details

Quality Control

Every batch of our 1-Bromo-2-(tert-Butyl)Benzene is produced under strict quality management protocols. We guarantee high chemical purity and lot-to-lot consistency through comprehensive analytical testing, including GC, HPLC, and NMR. A detailed Certificate of Analysis (COA) providing full specification results is provided with each shipment to ensure traceability and support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Density (at 20°C)	~1.25 g/cm³
Refractive Index (n20D)	~1.54

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.