Description

Diazoacetyl-Dl-Nle-Ome is a specialized, protected amino acid derivative featuring a diazoacetyl functional group. This compound is a critical building block in advanced organic synthesis, particularly for the preparation of peptide mimetics and enzyme inhibitors. It is essential for research and development chemists in the pharmaceutical and biotechnology sectors who require high-purity intermediates for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel peptide-based therapeutics and protease inhibitors.
• Bioconjugation Reagent: Used for site-specific labeling and cross-linking of biomolecules in biochemical research.
• Organic Synthesis Building Block: Employed in the construction of complex molecular architectures, leveraging its reactive diazo group for C-H insertion or cyclopropanation reactions.
• Chemical Biology Probe Development: Utilized to create activity-based probes for studying enzyme function and mechanism.
• Academic & Industrial R&D: Serves as a valuable tool for method development and exploring new synthetic pathways in medicinal chemistry.

Basic Information

Product Name	Diazoacetyl-Dl-Nle-Ome
CAS No.	7013-09-4
Molecular Formula	C9H15N3O3
Molecular Weight	213.24 g/mol
Synonyms	Diazoacetyl-DL-norleucine methyl ester; Methyl 2-diazoacetamido-4-methylpentanoate; DL-2-(Diazoacetamido)-4-methylpentanoic acid methyl ester; N-(Diazoacetyl)-DL-norleucine methyl ester; Diazoacetyl-norleucine-OMe; N-Diazoacetyl-DL-norleucine methyl ester; Acetic acid, 2-diazo-, 2-[(1-methoxy-4-methyl-1-oxopentan-2-yl)amino]-2-oxoethyl ester; 7013-09-4
EINECS	Contact for details

Quality Control

Our Diazoacetyl-Dl-Nle-Ome is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive nature, prolonged exposure to light should be avoided. Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder or crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.