Description

3-(1H-Benzoimidazol-2-Yl)-1,1,1-Trifluoro-Propan-2-One is a high-value trifluoromethyl ketone derivative featuring a benzimidazole moiety, making it a versatile and potent building block for advanced chemical synthesis. This compound is critical for researchers and manufacturers requiring precise molecular architecture to develop novel active ingredients. It is primarily utilized in the pharmaceutical and agrochemical industries for the research and development of new drug candidates and crop protection agents, where its unique structure imparts desirable biological and physicochemical properties.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of protease inhibitors, kinase inhibitors, and other small-molecule therapeutics.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the benzimidazole and trifluoromethyl groups.
• Material Science Precursor: Acts as a building block for advanced organic materials, including ligands for catalysis and monomers for specialty polymers.
• Biochemical Probe Development: Employed in medicinal chemistry to create tool compounds for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring fluorinated heterocyclic compounds.

Basic Information

Product Name	3-(1H-Benzoimidazol-2-Yl)-1,1,1-Trifluoro-Propan-2-One
CAS No.	782-55-8
Molecular Formula	C10H7F3N2O
Molecular Weight	228.17 g/mol
Synonyms	1,1,1-Trifluoro-3-(1H-benzimidazol-2-yl)propan-2-one; 2-Acetyl-2-trifluoromethyl-1H-benzimidazole; 3-(1H-Benzimidazol-2-yl)-1,1,1-trifluoropropan-2-one; 2-(Trifluoroacetyl)methylbenzimidazole; 2-(2-Oxo-3,3,3-trifluoropropyl)-1H-benzimidazole; 782-55-8; 3-(1H-Benzoimidazol-2-yl)-1,1,1-trifluoro-2-propanone
EINECS	Contact for details

Quality Control

Our 3-(1H-Benzoimidazol-2-Yl)-1,1,1-Trifluoro-Propan-2-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.