Description

1-(4-Chlorophenyl)-2,2,3,3,3-Pentafluoro-Propan-1-One is a high-value fluorinated aromatic ketone intermediate, distinguished by its unique combination of a chlorophenyl ring and a pentafluoropropyl group. This structure makes it a critical building block for synthesizing advanced materials and active pharmaceutical ingredients (APIs) where enhanced stability, lipophilicity, and specific electronic properties are required. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted functionalities.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing fluorinated motifs to improve metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atoms contribute to increased biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for high-performance displays.
• Organic Electronics: Employed in the synthesis of novel organic semiconductors and electron-transport materials.
• Advanced Polymer Modifiers: Acts as a monomer or cross-linking agent for creating specialty polymers with unique surface properties and chemical resistance.
• Chemical Research & Development: A versatile building block in academic and industrial labs for exploring new reactions in fluoroorganic chemistry.

Basic Information

Product Name	1-(4-Chlorophenyl)-2,2,3,3,3-Pentafluoro-Propan-1-One
CAS No.	781-97-5
Molecular Formula	C9H4ClF5O
Molecular Weight	258.57 g/mol
Synonyms	4'-Chloro-2,2,3,3,3-pentafluoropropiophenone; p-Chloro-α,α,β,β,β-pentafluoropropiophenone; 1-(4-Chlorophenyl)-2,2,3,3,3-pentafluoro-1-propanone; 2,2,3,3,3-Pentafluoro-1-(4-chlorophenyl)-1-propanone; 4-Chlorophenyl pentafluoroethyl ketone; Pentafluoro(4-chlorophenyl)acetone
EINECS	Contact for details

Quality Control

Every batch of 1-(4-Chlorophenyl)-2,2,3,3,3-Pentafluoro-Propan-1-One is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements of your synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (typically 15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.