Description

(S)-3-Phenylbutyric Acid CAS NO 772-15-6 is a high-purity chiral building block and intermediate of significant importance in asymmetric synthesis. Its defined stereochemistry is critical for producing enantiomerically pure compounds, ensuring consistent biological activity and regulatory compliance in final products. This compound is essential for research and production in the pharmaceutical, agrochemical, and advanced material sectors, where precise molecular architecture dictates performance.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in cardiovascular, neurological, and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators for enhanced efficacy and environmental safety.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric hydrogenation and C-C bond-forming reactions.
• Fine Chemical and Flavor/Fragrance Intermediate: Employed in the synthesis of complex molecules for specialty chemicals and aroma compounds.
• Academic and R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.
• Material Science: Potential monomer or modifier for creating polymers with specific chiral or functional properties.

Basic Information

Product Name	(S)-3-Phenylbutyric Acid
CAS No.	772-15-6
Molecular Formula	C10H12O2
Molecular Weight	164.20 g/mol
Synonyms	(S)-(-)-3-Phenylbutyric Acid; (S)-3-Phenylbutanoic Acid; (S)-β-Methylhydrocinnamic Acid; (3S)-3-Phenylbutanoic Acid; L-3-Phenylbutyric Acid; (S)-3-Phenylbutyrate; (S)-Phenylbutyric Acid; (S)-3-PBA
EINECS	212-248-9

Quality Control

Our (S)-3-Phenylbutyric Acid is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets exacting standards for chemical and enantiomeric purity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance in cGMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and heat sources. Due to its nature as a strong acid/organic solvent, handle with appropriate personal protective equipment in accordance with safety data sheet instructions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Melting Point	48 - 52 °C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.