Description

5-Trifluoromethyl-1,3,4-Oxadiazol-2-Ylamine is a high-value, heterocyclic organic compound featuring a trifluoromethyl-substituted oxadiazole core. This specialized chemical building block is prized for its unique electronic properties and structural rigidity, making it a critical intermediate in advanced synthetic chemistry. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for the synthesis of advanced polymers, liquid crystals, and electronic materials requiring specific fluorine-containing heterocycles.
• Chemical Biology & Proteomics: Employed as a specialized reagent or linker in the design of chemical probes and activity-based protein profiling (ABPP) agents.
• Organic Synthesis Building Block: Utilized in academic and industrial R&D for constructing complex molecular architectures, leveraging its reactive amine and stable oxadiazole ring.

Basic Information

Product Name	5-Trifluoromethyl-1,3,4-Oxadiazol-2-Ylamine
CAS No.	768-29-6
Molecular Formula	C3H2F3N3O
Molecular Weight	153.06 g/mol
Synonyms	2-Amino-5-(trifluoromethyl)-1,3,4-oxadiazole; 5-(Trifluoromethyl)-1,3,4-oxadiazol-2-amine; 2-Amino-5-trifluoromethyl-1,3,4-oxadiazole; 1,3,4-Oxadiazol-2-amine, 5-(trifluoromethyl)-; 5-Trifluoromethyl-2-amino-1,3,4-oxadiazole; α-(Trifluoromethyl)-1,3,4-oxadiazol-2-ylamine
EINECS	Contact for details

Quality Control

Our 5-Trifluoromethyl-1,3,4-Oxadiazol-2-Ylamine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.