Description

Benzene, 1-Ethynyl-4-Iodo- is a versatile halogenated aromatic building block characterized by its reactive ethynyl and iodo functional groups. This compound is critical for advanced organic synthesis, enabling efficient cross-coupling reactions and the construction of complex molecular architectures. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require high-purity intermediates for developing new active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) via Sonogashira, Heck, and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Material Science & Organic Electronics: Serves as a precursor for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), semiconductors, and sensors.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating molecular libraries.
• Liquid Crystal & Advanced Material Synthesis: Used as a rigid, functionalized core unit in the production of liquid crystal materials and other specialty polymers.

Basic Information

Product Name	Benzene, 1-Ethynyl-4-Iodo-
CAS No.	766-99-4
Molecular Formula	C8H5I
Molecular Weight	228.03 g/mol
Synonyms	4-Iodophenylacetylene; 1-Ethynyl-4-iodobenzene; p-Iodophenylacetylene; 4-Ethynyl-1-iodobenzene; (4-Iodophenyl)ethyne; 1-Iodo-4-ethynylbenzene; 4-Iodoethynylbenzene; 4-(Iodophenyl)acetylene
EINECS	Contact for details

Quality Control

Our production of Benzene, 1-Ethynyl-4-Iodo- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or otherwise opaque.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.