Description

1-Bromo-3-Ethynyl-Benzene is a versatile aromatic building block characterized by its bromine and ethynyl functional groups. This compound is crucial for advanced organic synthesis, particularly in cross-coupling reactions and the construction of complex molecular architectures. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries for developing active ingredients, functional polymers, and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via Sonogashira and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators.
• Material Science & Polymer Chemistry: Serves as a monomer or functionalizing agent for creating conductive polymers, liquid crystals, and advanced organic frameworks (MOFs/COFs).
• Chemical Research & Development: An essential reagent in academic and industrial R&D labs for exploring new organic transformations and constructing complex molecular scaffolds.
• Ligand & Catalyst Preparation: Employed in the synthesis of specialized ligands and organometallic catalysts used in homogeneous catalysis.
• Fine Chemical Production: A building block for manufacturing dyes, pigments, and other high-value specialty chemicals.

Basic Information

Item	Detail
Product Name	1-Bromo-3-Ethynyl-Benzene
CAS No.	766-81-4
Molecular Formula	C8H5Br
Molecular Weight	181.03 g/mol
Synonyms	3-Bromophenylacetylene; m-Bromophenylacetylene; 3-Ethynylbromobenzene; 1-Bromo-3-ethynylbenzene; 3-Bromoethynylbenzene; (3-Bromophenyl)ethyne; m-Bromoethynylbenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-Ethynyl-Benzene is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing specific results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.