Description

Methyl Cyclobutanecarboxylate is a versatile organic ester building block with a unique strained ring structure, offering significant value in advanced chemical synthesis. Its cyclobutane core provides a rigid, high-energy framework that is highly sought after for constructing complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials industries seeking novel intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring constrained, three-dimensional scaffolds to improve binding affinity and metabolic stability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the cyclobutane ring can enhance biological activity and environmental profile.
• Ligand and Catalyst Development: Employed in organometallic chemistry for creating specialized ligands that modify catalyst selectivity and activity in asymmetric synthesis.
• Fragrance and Flavor Chemistry: Acts as a starting material for synthesizing unique musk and woody odorants, leveraging the ester functionality and ring strain for specific olfactory notes.
• Polymer Science: Investigated as a monomer or cross-linking agent for producing polymers with tailored thermal and mechanical properties due to the strained ring system.
• Organic Synthesis Building Block: Utilized in ring-opening, functionalization, and [2+2] cycloaddition reactions to access a diverse array of carbocyclic and heterocyclic compounds.

Basic Information

Product Name	Methyl Cyclobutanecarboxylate
CAS No.	765-85-5
Molecular Formula	C7H12O2
Molecular Weight	128.17 g/mol
Synonyms	Cyclobutanecarboxylic acid, methyl ester; Methyl cyclobutanecarboxylate; Methyl cyclobutane-1-carboxylate; Cyclobutanecarboxylic acid methyl ester; Methyl ester of cyclobutanecarboxylic acid; NSC 66429
EINECS	212-155-5

Quality Control

Our Methyl Cyclobutanecarboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (IR, NMR), to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (20°C)	1.428 - 1.432
Density (20°C)	1.00 - 1.04 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.