Description

Ethyl 2-Cyano-3-Methylcrotonate is a versatile cyanoacrylate ester derivative, serving as a key synthetic intermediate in the production of pharmaceuticals and agrochemicals. Its value lies in its reactive cyano and ester functional groups, which enable efficient construction of complex heterocyclic and acyclic frameworks. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing pyridine, pyrimidine, and other nitrogen-containing heterocycles found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and insecticides, particularly those requiring cyanoacrylate backbones.
• Fine Chemical Production: Serves as a precursor for dyes, pigments, and specialty polymers where its structure imparts specific chemical properties.
• Research & Development: Employed in academic and industrial labs for method development and the discovery of novel chemical entities.
• Chemical Synthesis: Utilized in Knoevenagel condensation and Michael addition reactions to form carbon-carbon bonds.

Basic Information

Product Name	Ethyl 2-Cyano-3-Methylcrotonate
CAS No.	759-58-0
Molecular Formula	C8H11NO2
Molecular Weight	153.18 g/mol
Synonyms	Ethyl 2-Cyano-3-methylbut-2-enoate; 2-Cyano-3-methylcrotonic Acid Ethyl Ester; Ethyl 2-Cyano-3-methyl-2-butenoate; 3-Methyl-2-cyanocrotonic Acid Ethyl Ester; NSC 404058; Ethyl α-Cyano-β-methylcrotonate; 2-Butenoic acid, 2-cyano-3-methyl-, ethyl ester
EINECS	212-073-6

Quality Control

Our Ethyl 2-Cyano-3-Methylcrotonate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Refractive Index	1.460 - 1.470
Density	1.05 - 1.10 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.