Description

Hexafluoro-Dl-Valine is a fluorinated derivative of the amino acid valine, characterized by the substitution of all six hydrogen atoms on its two methyl groups with fluorine atoms. This unique fluorination pattern significantly alters its physicochemical properties, making it a valuable building block for advanced materials and pharmaceutical research. It is primarily utilized by researchers and manufacturers in the fields of medicinal chemistry, peptide science, and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated peptides and bioactive molecules, enhancing metabolic stability and lipophilicity.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to investigate the effects of fluorination on drug potency and pharmacokinetics.
• Peptide Modification: Incorporated into peptide sequences to create fluorinated analogs with improved membrane permeability and resistance to enzymatic degradation.
• Material Science: Serves as a precursor for fluorinated surfaces, coatings, or specialty polymers requiring specific hydrophobic and oleophobic characteristics.
• Agrochemical Development: Potential use in the synthesis of novel fluorinated active ingredients for crop protection.
• Biochemical Probe: Utilized as a labeled or tagged amino acid in biochemical assays and imaging studies.

Basic Information

Product Name	Hexafluoro-Dl-Valine
CAS No.	759-12-6
Molecular Formula	C5H5F6NO2
Molecular Weight	225.09 g/mol
Synonyms	DL-Hexafluorovaline; 2-Amino-3,3,4,4,5,5,5-heptafluoropentanoic Acid (common misnomer); 2-Amino-3,3,4,4,5,5,5-heptafluoro-valeric Acid; (±)-Hexafluorovaline; (RS)-Hexafluorovaline; 3,3,4,4,5,5,5-Heptafluoro-DL-valine; 759-12-6; UNII-2R6Q8QZ5PJ
EINECS	Contact for details

Quality Control

Our Hexafluoro-Dl-Valine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and specific tests for residual solvents and moisture. A Certificate of Analysis (COA) detailing all specifications and results is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.