Description

3-Methyl-2-Oxobutyric Acid is a key organic acid and keto acid derivative, also known as 2-Ketoisovaleric acid. This compound serves as a crucial building block and intermediate in the synthesis of more complex molecules, including pharmaceuticals, agrochemicals, and fine chemicals. It is primarily utilized by research institutions, pharmaceutical developers, and specialty chemical manufacturers for process development and active ingredient synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those involving branched-chain amino acid analogs.
• Biochemical Research: Used as a substrate or standard in metabolic pathway studies, especially related to valine and leucine biosynthesis and degradation.
• Fine Chemical Synthesis: Serves as a versatile building block for producing flavors, fragrances, and other specialty organic compounds.
• Agrochemical Development: Employed in the research and production of advanced herbicides, pesticides, and plant growth regulators.
• Nutritional Science: Studied in relation to metabolic disorders (e.g., Maple Syrup Urine Disease) as 2-ketoisovaleric acid is a diagnostic metabolite.

Basic Information

Product Name	3-Methyl-2-Oxobutyric Acid
CAS No.	759-05-7
Molecular Formula	C5H8O3
Molecular Weight	116.12 g/mol
Synonyms	2-Ketoisovaleric Acid; 2-Oxoisovaleric Acid; 3-Methyl-2-oxobutanoic Acid; α-Ketoisovaleric Acid; 2-Keto-3-methylbutyric Acid; Isobutylglyoxylic Acid; 2-Oxo-3-methylbutanoic Acid; (CH3)2CHCOCOOH
EINECS	212-062-1

Quality Control

Our 3-Methyl-2-Oxobutyric Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure high purity, identity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment supports applications requiring reliable and traceable raw materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its acidic nature, store separately from strong bases, oxidizers, and reactive metals. Ensure containers are kept upright and properly labeled.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	30 - 34 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.