Description

Methyl 2,3,3-trifluoro-3-methoxypropanoate is a versatile fluorinated building block and specialty ester. This compound is valued for its unique trifluoromethyl and methoxy functional groups, which are critical for modulating the physicochemical properties of target molecules. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for introducing fluorine atoms into bioactive molecules, enhancing metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides where fluorine substitution improves efficacy and environmental profile.
• Liquid Crystal & Electronic Materials: Serves as a precursor for fluorinated components in display technologies and dielectric fluids.
• Organic Synthesis Building Block: Employed in nucleophilic substitution and coupling reactions to construct complex fluorinated architectures.
• Polymer Modification: Incorporated to create specialty fluoropolymers with enhanced chemical resistance and surface properties.

Basic Information

Product Name	Methyl 2,3,3-Trifluoro-3-Methoxypropanoate
CAS No.	758-69-0
Molecular Formula	C5H7F3O3
Molecular Weight	172.10 g/mol
Synonyms	Methyl 3-methoxy-2,3,3-trifluoropropanoate; 2,3,3-Trifluoro-3-methoxypropanoic acid methyl ester; 3-Methoxy-2,3,3-trifluoropropionic acid methyl ester; Methyl 3-methoxy-2,3,3-trifluoropropionate; Trifluoromethoxypropanoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2,3,3-Trifluoro-3-Methoxypropanoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for all shipments to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place away from incompatible materials such as strong bases and fluorides. Due to its highly volatile nature, keep containers tightly sealed and handle in a fume hood. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	≤ 1.0% total

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.