Description

Bis(2,2,2-trifluoroethyl) methylphosphonate is a specialized organophosphorus compound featuring trifluoroethyl groups. This structure is significant for its role as a key intermediate and reagent in advanced chemical synthesis, particularly in the development of pharmaceuticals and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring phosphonate or fluorine-containing motifs for enhanced bioactivity and metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, insecticides, and fungicides where the phosphonate group acts as a bioisostere or contributes to the mode of action.
• Ligand and Catalyst Precursor: Serves as a starting material for the preparation of specialized phosphonate-based ligands used in asymmetric catalysis and metal complexation.
• Flame Retardant Additive Research: Investigated as a potential component or synergist in flame-retardant formulations for polymers and textiles due to its phosphorus and fluorine content.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new reactions, such as Horner-Wadsworth-Emmons olefinations or Michael additions, to create novel fluorinated compounds.
• Electrolyte Additive for Batteries: Studied for use as a functional additive in lithium-ion battery electrolytes to improve interfacial stability and cycle life.

Basic Information

Product Name	Bis(2,2,2-trifluoroethyl) methylphosphonate
CAS No.	757-95-9
Molecular Formula	C7H9F6O3P
Molecular Weight	286.11 g/mol
Synonyms	Methylphosphonic acid bis(2,2,2-trifluoroethyl) ester; Bis(2,2,2-trifluoroethyl) methylphosphonate; Phosphonic acid, methyl-, bis(2,2,2-trifluoroethyl) ester; Methyl bis(2,2,2-trifluoroethyl) phosphonate; 2,2,2-Trifluoroethyl methylphosphonate; (Methoxyphosphinyl)bis(2,2,2-trifluoroethane)
EINECS	212-052-9

Quality Control

Our Bis(2,2,2-trifluoroethyl) methylphosphonate is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing assay and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and fluorides. The container must be kept tightly closed in a dry and well-ventilated place. Contents are moisture-sensitive.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.45 g/mL
Refractive Index (n20D)	~1.355

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.