Description

Diethyl 2-Bromo-2-Fluoro-Malonate is a versatile fluorinated building block and a key intermediate in organic synthesis. This compound is valued for its ability to introduce both bromine and fluorine atoms into target molecules, enabling the synthesis of complex fluorinated structures. It is primarily used by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries for developing new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing fluorinated active pharmaceutical ingredients (APIs), particularly in antiviral and anticancer drug discovery.
• Agrochemical Synthesis: Used in the production of novel fluorinated pesticides and herbicides, where the fluorine atom enhances biological activity and stability.
• Fluorinated Material Precursor: Serves as a starting material for creating specialty polymers, liquid crystals, and other advanced materials with unique properties.
• Organic Synthesis Reagent: Employed in palladium-catalyzed cross-coupling reactions and other transformations to construct complex organic molecules.
• Chemical Research & Development: A valuable tool for medicinal chemists and researchers exploring new chemical entities and reaction pathways.

Basic Information

Product Name	Diethyl 2-Bromo-2-Fluoro-Malonate
CAS No.	756-44-5
Molecular Formula	C7H10BrFO4
Molecular Weight	241.06 g/mol
Synonyms	Diethyl bromofluoromalonate; 2-Bromo-2-fluoromalonic acid diethyl ester; Bromofluoromalonic acid diethyl ester; Ethyl 2-bromo-2-fluoromalonate; Diethyl (bromofluoro)propanedioate; Propanedioic acid, 2-bromo-2-fluoro-, 1,3-diethyl ester; 756-44-5; NSC 406925
EINECS	Contact for details

Quality Control

Our Diethyl 2-Bromo-2-Fluoro-Malonate is produced under a strict quality management system to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including GC/HPLC for assay and purity determination. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be kept under an inert atmosphere if opened for prolonged periods to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.