Description

1,1,2,2-Tetrafluoro-1,4-diiodobutane is a specialized fluorinated organic compound that serves as a versatile building block in advanced chemical synthesis. Its unique structure, featuring both perfluoroalkyl and iodine functional groups, makes it a valuable precursor for introducing fluorinated segments into target molecules, thereby modifying their physical and chemical properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications ranging from novel drug candidates to specialty polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: Used in the synthesis of fluorinated active pharmaceutical ingredients (APIs) to enhance metabolic stability, bioavailability, and membrane permeability.
• Agrochemical Synthesis: Serves as a key fluorinating agent in creating novel herbicides, pesticides, and fungicides with improved efficacy and environmental profiles.
• Liquid Crystal Materials: Acts as a core component in the production of fluorinated liquid crystals for advanced display technologies (LCDs).
• Polymer & Material Science: Employed as a monomer or modifier in the synthesis of specialty fluoropolymers, coatings, and surfactants with unique surface properties and chemical resistance.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Negishi, Kumada) and nucleophilic substitutions to construct complex fluorinated organic architectures.
• Research & Development: A critical reagent in academic and industrial R&D for exploring new fluorination methodologies and creating novel fluorinated compounds.

Basic Information

Product Name	1,1,2,2-Tetrafluoro-1,4-diiodobutane
CAS No.	755-95-3
Molecular Formula	C4H2F4I2
Molecular Weight	371.86 g/mol
Synonyms	1,4-Diiodoperfluorobutane; 1,4-Diiodotetrafluorobutane; Tetrafluoro-1,4-diiodobutane; Perfluoro-1,4-diiodobutane; 1,1,2,2-Tetrafluoro-1,4-diiodo-butane; Butane, 1,1,2,2-tetrafluoro-1,4-diiodo-; 1,4-Diiodo-1,1,2,2-tetrafluorobutane; 1,4-Bis(iodo)tetrafluorobutane
EINECS	212-048-9

Quality Control

Our 1,1,2,2-Tetrafluoro-1,4-diiodobutane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing assay, impurity profile, and physical properties is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its sensitivity to strong acids and organic solvents, store separately from incompatible materials. Handle and store under an inert atmosphere if specified for high-purity grades.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~2.5 g/mL
Refractive Index (n20D)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.