Description

Methyl 2,2,3,3-tetrafluoro-3-methoxypropionate is a specialized fluorinated ester building block, valued for its unique combination of a reactive ester group and a fluorinated methoxy ether moiety. This compound is critical for introducing fluorine atoms and specific functional handles into target molecules, enhancing properties like metabolic stability, lipophilicity, and chemical resistance. It is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients and performance chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for incorporating fluorinated motifs into drug candidates to improve bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the development of novel fluorinated pesticides and herbicides with enhanced activity and environmental profile.
• Fluorinated Polymer & Material Science: Serves as a monomer or modifier for creating specialty polymers with unique surface properties, chemical resistance, and low refractive indices.
• Organic Synthesis Building Block: Employed in nucleophilic substitution or hydrolysis reactions to access fluorinated acids, alcohols, and other derivatives.
• Liquid Crystal & Electronic Chemicals: Potential use in the synthesis of fluorinated components for display technologies and dielectric fluids.

Basic Information

Product Name	Methyl 2,2,3,3-Tetrafluoro-3-Methoxypropionate
CAS No.	755-73-7
Molecular Formula	C6H6F4O3
Molecular Weight	202.10 g/mol
Synonyms	Methyl 3-methoxy-2,2,3,3-tetrafluoropropanoate; 2,2,3,3-Tetrafluoro-3-methoxypropionic Acid Methyl Ester; Methyl Perfluoromethoxyacetate; Methyl Tetrafluoromethoxyacetate; MFMP; 3-Methoxy-2,2,3,3-tetrafluoropropionic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of Methyl 2,2,3,3-Tetrafluoro-3-Methoxypropionate is produced and tested under a strict quality management system. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles, typically determined by GC, HPLC, NMR, and FTIR. Our quality commitment ensures the consistency and reliability required for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong bases. Due to its highly volatile nature, ensure containers are securely sealed. Recommended storage temperature is 2-8°C for long-term stability, though short-term storage at 15-25°C is acceptable.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.