Description

1,1,1,3,3,3-Hexafluoro-2-Phenyl-2-Propanol is a high-purity fluorinated alcohol derivative, serving as a versatile and critical building block in advanced chemical synthesis. Its unique structure, featuring a trifluoromethylated phenyl group, provides exceptional properties for modifying reactivity and physical characteristics in target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials industries seeking to incorporate fluorine for enhanced bioactivity, stability, or material performance.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in the synthesis of compounds where fluorine substitution is used to modulate metabolism, bioavailability, and receptor binding.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the introduction of fluorine atoms can significantly increase efficacy and environmental stability.
• Liquid Crystal & OLED Materials: Acts as a precursor or modifying agent in the synthesis of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, contributing to improved electronic properties and thermal stability.
• Polymer & Resin Modifier: Employed to introduce fluorinated side chains into polymers, enhancing properties such as chemical resistance, hydrophobicity, and lowering the dielectric constant for electronic applications.
• Catalyst & Ligand Precursor: Serves as a starting material for creating specialized ligands and catalysts used in asymmetric synthesis and other high-value chemical transformations.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new fluorination methodologies and creating novel chemical entities with tailored properties.

Basic Information

Product Name	1,1,1,3,3,3-Hexafluoro-2-Phenyl-2-Propanol
CAS No.	718-64-9
Molecular Formula	C9H6F6O
Molecular Weight	244.13 g/mol
Synonyms	Hexafluoro-2-phenyl-2-propanol; α,α-Bis(trifluoromethyl)benzyl alcohol; (Perfluoro-tert-butyl)benzyl alcohol; 2-Phenyl-1,1,1,3,3,3-hexafluoro-2-propanol; Phenylbis(trifluoromethyl)methanol; HFIP (Note: HFIP commonly refers to 1,1,1,3,3,3-Hexafluoro-2-propanol, but this is the phenyl-substituted analog); Benzyl alcohol, α,α-bis(trifluoromethyl)-; 718-64-9
EINECS	211-957-8

Quality Control

Our 1,1,1,3,3,3-Hexafluoro-2-Phenyl-2-Propanol is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopy (NMR, IR), to ensure high purity and consistent composition suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We support compliance with relevant regulatory frameworks, including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). To prevent degradation, containers should be kept tightly sealed and under an inert atmosphere (e.g., nitrogen) after opening. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.