Description

4,4-Bis(Trifluoromethyl)Bicyclo[3.2.0]Hepta-2,6-Diene is a highly fluorinated bicyclic diene compound, serving as a valuable and versatile building block in advanced organic synthesis. Its core value lies in the unique reactivity of its strained ring system combined with the strong electron-withdrawing effect of the trifluoromethyl groups, making it an exceptional precursor for creating complex fluorinated molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials industries for applications requiring the introduction of fluorine atoms to modulate the properties of target molecules.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs) with enhanced metabolic stability, bioavailability, and lipophilicity.
• Agrochemical Synthesis: Building block for creating advanced herbicides, fungicides, and pesticides where fluorination improves efficacy and environmental persistence profiles.
• Material Science Research: Precursor for synthesizing fluorinated polymers, liquid crystals, and electronic materials with unique dielectric and surface properties.
• Catalysis & Ligand Development: Used to construct sophisticated, fluorinated ligands for transition metal catalysis, enabling new reaction pathways.
• Organic Synthesis Reagent: Employed in Diels-Alder and other cycloaddition reactions to construct complex, polycyclic, and fluorinated organic frameworks.
• Fluorine Chemistry Research: A critical compound for academic and industrial research exploring new methodologies in fluorination and the chemistry of strained, fluorinated systems.

Basic Information

Product Name	4,4-Bis(Trifluoromethyl)Bicyclo[3.2.0]Hepta-2,6-Diene
CAS No.	714-64-7
Molecular Formula	C9H6F6
Molecular Weight	228.14 g/mol
Synonyms	4,4-Bis(trifluoromethyl)bicyclo[3.2.0]hepta-2,6-diene; 4,4-Bis(trifluoromethyl)-2,6-heptadiene, bicyclo[3.2.0] form; Bicyclo[3.2.0]hepta-2,6-diene, 4,4-bis(trifluoromethyl)-; 4,4-Bis(trifluoromethyl)-2,6-bicyclo[3.2.0]heptadiene; 4,4-Bis(trifluoromethyl)-2,6-diene bicyclo[3.2.0]heptane derivative; 4,4-Bis(trifluoromethyl)-2,6-heptadiene (bicyclic); 714-64-7 (CAS Registry)
EINECS	Contact for details

Quality Control

Our 4,4-Bis(Trifluoromethyl)Bicyclo[3.2.0]Hepta-2,6-Diene is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes comprehensive analytical characterization, including NMR (1H, 19F, 13C), GC-MS, and HPLC analysis. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place, away from incompatible materials such as strong acids and bases. Due to its highly volatile nature, ensure containers are securely sealed and stored at recommended temperatures (typically 2-8°C or as specified on the label) to maintain stability and prevent loss.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 95.0% (Area %)
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.