Description

2-(Difluoromethoxy)Naphthalene is a specialized fluorinated aromatic building block, a key intermediate in advanced organic synthesis. Its value lies in the unique reactivity imparted by the difluoromethoxy group, enabling the development of novel compounds with enhanced properties. This high-purity intermediate is essential for research and production in the pharmaceutical and agrochemical industries, where it is used to create active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring fluorinated motifs to modulate bioavailability, metabolic stability, and receptor binding.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the difluoromethoxy group can enhance biological activity and environmental persistence profiles.
• Liquid Crystal Materials: Serves as a core component in the synthesis of fluorinated liquid crystals for advanced display technologies (LCDs), contributing to improved dielectric anisotropy and thermal stability.
• Organic Electronic Materials: Acts as a precursor for electron-transport materials or host materials in organic light-emitting diodes (OLEDs) and other electronic devices.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and material science R&D, enabling structure-activity relationship (SAR) studies and the exploration of new chemical spaces.
• Specialty Polymer Modifier: Can be incorporated into polymer chains to impart specific characteristics such as altered solubility, thermal resistance, or optical properties.

Basic Information

Product Name	2-(Difluoromethoxy)Naphthalene
CAS No.	712-79-8
Molecular Formula	C₁₁H₈F₂O
Molecular Weight	194.18 g/mol
Synonyms	2-(Difluoromethoxy)naphthalene; 2-Naphthyl difluoromethyl ether; Naphthalene, 2-(difluoromethoxy)-; 1-(Difluoromethoxy)naphthalene (isomer); α-Naphthyl difluoromethyl ether; Difluoromethoxynaphthalene; 712-79-8; EINECS 211-925-7
EINECS	211-925-7

Quality Control

Every batch of 2-(Difluoromethoxy)Naphthalene is manufactured and tested under a strict quality management system. We ensure high chemical purity and consistency through advanced analytical techniques including GC, HPLC, and NMR. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to guarantee compliance with your specific R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.