Description

E/Z-1-Iodo-2-(Pentafluoroethyl)Cyclohexane is a high-value fluorinated organic intermediate characterized by its unique combination of a cyclohexane ring, an iodine substituent, and a pentafluoroethyl group. This compound matters for its role as a versatile building block in advanced synthesis, enabling the introduction of both fluorine and iodine functionalities into target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials industries for creating novel compounds with tailored properties.

Application

• Pharmaceutical Intermediate: Used in the synthesis of fluorinated drug candidates, particularly in medicinal chemistry programs targeting metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a key precursor for developing novel fluorinated pesticides and herbicides with enhanced activity and environmental profile.
• Liquid Crystal & OLED Materials: Employed in the research and production of fluorinated components for electronic display technologies.
• Advanced Polymer Modification: Acts as a monomer or grafting agent for introducing fluorine into polymers to improve chemical resistance and surface properties.
• Cross-Coupling Reactions: Utilized as an electrophilic coupling partner in palladium-catalyzed reactions (e.g., Suzuki, Heck) to construct complex fluorinated architectures.
• Radiolabeling Precursor: The iodine atom provides a potential handle for isotopic labeling (e.g., with I-125) in tracer studies for life science research.

Basic Information

Item	Detail
Product Name	E/Z-1-Iodo-2-(Pentafluoroethyl)Cyclohexane
CAS No.	711-17-1
Molecular Formula	C8H10F5I
Molecular Weight	328.07 g/mol
Synonyms	1-Iodo-2-(pentafluoroethyl)cyclohexane; 2-(Pentafluoroethyl)cyclohexyl iodide; (Pentafluoroethyl)cyclohexyl iodide; Cyclohexane, 1-iodo-2-(pentafluoroethyl)-; 711-17-1; NSC 406924; 1-Iodo-2-(1,1,2,2,2-pentafluoroethyl)cyclohexane
EINECS	Contact for details

Quality Control

Our E/Z-1-Iodo-2-(Pentafluoroethyl)Cyclohexane is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider maintaining under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (E/Z mixture)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.