Description

2-Propen-1-One, 2,3,3-Trifluoro-1-Phenyl- is a specialized fluorinated α,β-unsaturated ketone, serving as a critical building block in advanced organic synthesis. Its unique trifluoromethyl-substituted structure offers significant value in modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. This high-purity intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, including protease inhibitors and kinase inhibitors, where the trifluoromethyl group enhances bioavailability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, leveraging fluorine's ability to improve compound activity and environmental persistence.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with tailored surface properties and chemical resistance.
• Liquid Crystal & OLED Materials: A valuable synthon for creating fluorinated aromatic cores that improve the dielectric anisotropy and stability of advanced electronic display materials.
• Fluorine Chemistry Research: An important reagent for studying nucleophilic addition reactions to fluorinated enones and exploring new fluorination methodologies.

Basic Information

Product Name	2-Propen-1-One, 2,3,3-Trifluoro-1-Phenyl-
CAS No.	708-87-2
Molecular Formula	C9H5F3O
Molecular Weight	186.13 g/mol
Synonyms	2,3,3-Trifluoro-1-phenyl-2-propen-1-one; 1-Phenyl-2,3,3-trifluoroprop-2-en-1-one; 2,3,3-Trifluoro-1-phenylprop-2-en-1-one; 3,3,3-Trifluoro-1-phenyl-2-propenone; (E/Z)-2,3,3-Trifluoro-1-phenylprop-2-en-1-one; α,β,β-Trifluorochalcone; Trifluoromethyl styryl ketone; Phenyl trifluoropropenone
EINECS	Contact for details

Quality Control

Our production of 2-Propen-1-One, 2,3,3-Trifluoro-1-Phenyl- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. All material is characterized and released against comprehensive specifications, including identity confirmation by FT-IR and NMR, and purity determination by GC or HPLC. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly sealed to prevent moisture ingress and potential decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.