Description

2-Hydroxy-1-Naphthaldehyde is a versatile aromatic aldehyde derivative of naphthalene, serving as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both a phenolic hydroxyl and an aldehyde group, makes it a valuable precursor for creating complex heterocyclic compounds and functional materials. This high-purity intermediate is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with naphthalene-based structures, such as certain anti-inflammatory and antimicrobial agents.
• Agrochemical Synthesis: Used in the manufacture of advanced pesticides, herbicides, and plant growth regulators, where it acts as a core scaffold for bioactive molecules.
• Dye and Pigment Manufacturing: Serves as a starting material for producing azo dyes, fluorescent dyes, and complex organic pigments, contributing to color strength and stability.
• Ligand and Chelating Agent: Functions as a versatile ligand in coordination chemistry for metal complexation, useful in catalysis, material science, and analytical chemistry.
• Organic Synthesis Building Block: Employed in Schiff base formation, condensation reactions, and the synthesis of heterocycles like benzofurans and naphthopyrans.
• Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic methodologies and developing novel chemical entities.

Basic Information

Product Name	2-Hydroxy-1-Naphthaldehyde
CAS No.	708-06-5
Molecular Formula	C11H8O2
Molecular Weight	172.18 g/mol
Synonyms	2-Hydroxynaphthalene-1-carbaldehyde; 1-Formyl-2-naphthol; 2-Naphthol-1-carboxaldehyde; 2-Hydroxy-1-naphthalenecarboxaldehyde; β-Hydroxy-α-naphthaldehyde; Aldehyde B; 1-Naphthaldehyde, 2-hydroxy-; 2-Hydroxy-1-naphthoic aldehyde
EINECS	211-904-8

Quality Control

Our 2-Hydroxy-1-Naphthaldehyde is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all test results are provided with every shipment. We adhere to cGMP principles where applicable, ensuring our product meets the stringent requirements of pharmaceutical and advanced synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame. For long-term storage, consider packaging under an inert gas such as nitrogen or argon to maintain optimal purity.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	78°C - 82°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.