Description

2,4-Dichloro-5-Fluoroacetophenone is a versatile and high-purity fluorinated aromatic ketone building block. Its molecular structure makes it a critical intermediate in the synthesis of complex, high-value molecules, particularly in the pharmaceutical sector. This compound is essential for research and manufacturing chemists in the agrochemical, pharmaceutical, and advanced material industries seeking to introduce specific halogenated motifs into their target compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially fluoroquinolone antibiotics and other fluorinated drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the dichloro-fluoro substitution pattern confers specific biological activity.
• Organic Synthesis Building Block: Serves as a versatile starting material for Friedel-Crafts acylation reactions and further functionalization to create complex aromatic systems.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and organic electronic materials due to its halogenated aromatic core.
• Chemical Research & Development: A valuable reagent for method development and exploring new synthetic pathways in academic and industrial R&D laboratories.

Basic Information

Product Name	2,4-Dichloro-5-Fluoroacetophenone
CAS No.	704-10-9
Molecular Formula	C8H5Cl2FO
Molecular Weight	207.03 g/mol
Synonyms	1-(2,4-Dichloro-5-fluorophenyl)ethan-1-one; 2',4'-Dichloro-5'-fluoroacetophenone; 5-Fluoro-2,4-dichloroacetophenone; Acetophenone, 2,4-dichloro-5-fluoro-; 2,4-Dichloro-5-fluorophenyl methyl ketone; 704-10-9; NSC 403119
EINECS	Contact for details

Quality Control

Our 2,4-Dichloro-5-Fluoroacetophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent composition. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports applications requiring reliable and traceable raw materials for GMP or research purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	68°C - 72°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.