Description

1-Propanone, 2,2-Difluoro-1-Phenyl- (9Ci) is a specialized fluorinated aromatic ketone building block, identified by CAS number 703-17-3. This compound is valued for its unique molecular structure, which introduces fluorine atoms to enhance the reactivity, stability, and lipophilicity of target molecules. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing difluoromethyl ketone motifs.
• Agrochemical Synthesis: Used in creating advanced pesticides and herbicides where the fluorine atoms improve biological activity and environmental stability.
• Material Science Research: Serves as a precursor for specialty polymers and advanced organic materials with tailored properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic additions, and as a precursor for heterocyclic compounds in academic and industrial R&D.
• Ligand and Catalyst Development: Useful for synthesizing novel ligands and organocatalysts used in asymmetric synthesis.
• Fluorine Chemistry Studies: A valuable compound for investigating the effects of fluorine substitution on reaction pathways and molecular properties.

Basic Information

Product Name	1-Propanone, 2,2-Difluoro-1-Phenyl- (9Ci)
CAS No.	703-17-3
Molecular Formula	C9H8F2O
Molecular Weight	170.16 g/mol
Synonyms	2,2-Difluoro-1-phenylethanone; 2,2-Difluoroacetophenone; α,α-Difluoroacetophenone; Phenyldifluoromethyl ketone; Difluoroacetophenone; 1-Phenylethanone, 2,2-difluoro-; (Difluoroacetyl)benzene; EINECS 211-882-1
EINECS	211-882-1

Quality Control

Our 1-Propanone, 2,2-Difluoro-1-Phenyl- is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles against our stringent specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials. The container should be kept tightly sealed to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.