Description

Cyclopropane-1,2-Dicarboxylic Acid Dimethyl Ester is a high-purity, versatile diester building block essential for advanced organic synthesis. This compound matters for its rigid, strained cyclopropane ring system, which is a key structural motif in the development of novel pharmaceuticals, agrochemicals, and functional materials. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate unique three-membered ring geometry into their target molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing strained ring systems for enhanced biological activity.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides where the cyclopropane moiety can improve efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a starting material for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer & Material Science: Employed as a monomer or cross-linking agent to introduce rigidity and unique thermal properties into specialty polymers and advanced materials.
• Organic Synthesis Building Block: Utilized in [2+1] cycloadditions, ring-opening reactions, and as a scaffold for constructing complex, polycyclic molecular architectures in academic and industrial research.
• Flavor & Fragrance Industry: Potential intermediate for synthesizing specific aroma compounds with unique structural characteristics.

Basic Information

Product Name	Cyclopropane-1,2-Dicarboxylic Acid Dimethyl Ester
CAS No.	702-28-3
Molecular Formula	C7H10O4
Molecular Weight	158.15 g/mol
Synonyms	Dimethyl Cyclopropane-1,2-dicarboxylate; 1,2-Cyclopropanedicarboxylic Acid Dimethyl Ester; Dimethyl 1,2-Cyclopropanedicarboxylate; Methyl Cyclopropane-1,2-dicarboxylate; Cyclopropane-1,2-dicarboxylic Acid Methyl Ester; NSC 66495; Cyclopropanedicarboxylic Acid Dimethyl Ester
EINECS	211-874-1

Quality Control

Our Cyclopropane-1,2-Dicarboxylic Acid Dimethyl Ester is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing purity, physical properties, and impurity profiles are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Specific Gravity (20°C)	1.15 - 1.20
Refractive Index (n20D)	1.440 - 1.450

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.