Description

(1S,αs)-1,2,3,4,4A,7-Hexahydro-1β-Hydroxy-α,4Aα,8-Trimethyl-7-Oxonaphthalene-2α-Acetic Acid is a high-purity, specialized chemical intermediate with a complex fused-ring structure. This compound is valued for its role as a key chiral building block in advanced organic synthesis, particularly for the development of pharmaceuticals and fine chemicals. It is essential for research and production teams in the pharmaceutical, agrochemical, and advanced material sectors seeking to introduce specific stereochemistry and functional complexity into target molecules.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of complex drug candidates, especially steroids and terpenoid-based therapeutics.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where specific stereochemistry impacts biological activity.
• Fine Chemical Production: Serves as a building block for creating specialty chemicals, flavors, and fragrances requiring precise molecular architecture.
• Academic & Industrial Research: A valuable reagent for methodological studies in organic chemistry, asymmetric synthesis, and catalysis.
• Material Science: Potential intermediate in the development of specialized polymers or liquid crystals with tailored properties.

Basic Information

Product Name	(1S,αs)-1,2,3,4,4A,7-Hexahydro-1β-Hydroxy-α,4Aα,8-Trimethyl-7-Oxonaphthalene-2α-Acetic Acid
CAS No.	79-59-4
Molecular Formula	C₁₅H₂₂O₄
Molecular Weight	266.33 g/mol
Synonyms	2-[(1S,4aS,8aR)-1-Hydroxy-4a,8-dimethyl-7-oxo-1,2,3,4,4a,5,6,8a-octahydronaphthalen-1-yl]acetic acid; Podocarpic Acid; 13-Hydroxy-8(14)-podocarpen-18-oic Acid; 8(14)-Podocarpen-13-ol-18-oic Acid; NSC 122047; 1-Naphthaleneacetic acid, 1,2,3,4,4a,5,6,8a-octahydro-1-hydroxy-4a,8-dimethyl-7-oxo-, (1S,4aS,8aR)-
EINECS	201-211-6

Quality Control

Our (1S,αs)-1,2,3,4,4A,7-Hexahydro-1β-Hydroxy-α,4Aα,8-Trimethyl-7-Oxonaphthalene-2α-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to light and propensity for oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after the container has been opened. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.