Description

Quassin CAS NO 76-78-8 is a highly oxygenated, bitter-tasting triterpenoid lactone primarily isolated from the wood of the *Quassia amara* tree. This compound is valued for its potent biological activity, serving as a key reference standard and active ingredient in research and development. It is essential for industries focused on natural product chemistry, pharmacology, and agrochemicals. Professionals rely on it for its consistent purity and well-characterized properties in analytical and formulation work.

Application

• Pharmaceutical Research & Development: Used as a reference standard in HPLC and LC-MS analysis for quality control of herbal extracts and botanical drug substances.
• Natural Product Isolation: Serves as a key marker compound for the identification and standardization of *Quassia amara* and related Simaroubaceae plant extracts.
• Biological Activity Studies: Employed in bioassays to investigate its well-documented anthelmintic, antimalarial, insecticidal, and potential anticancer properties.
• Agrochemical Formulations: Acts as a natural bittering agent and botanical insecticide in the development of eco-friendly pest control products.
• Bitterant for Denaturation: Utilized in industrial applications to denature alcohol and other substances, making them unfit for human consumption.
• Nutraceutical Standardization: Used to assay and standardize bitter tonic dietary supplements derived from quassia wood.

Basic Information

Product Name	Quassin
CAS No.	76-78-8
Molecular Formula	C22H28O6
Molecular Weight	388.46 g/mol
Synonyms	Quassine; (3aS,6aR,7aS,8S,10aS,10bS,10cS)-8-Hydroxy-2,2,6a,10b-tetramethyl-1,3,3a,4,5,6,6a,7,7a,8,9,10,10a,10b,10c-hexadecahydro-2H-8,10c-methanocyclohepta[cd]pentalen-11(2H)-one; 2,12-Dihydroxy-6a,12b-dimethyl-2-[(2R,4aS,6aS,12bR,14aS,14bS)-2,4a,6a,9,12b,14a-hexamethyl-1,2,3,4,4a,5,6,6a,11,12,12b,13,14,14a,14b-pentadecahydropicen-3-yl]-3H-naphtho[2,1-b]pyran-3-one; Nigakilactone D; NSC 146051
EINECS	200-985-9

Quality Control

Our Quassin is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods (IR, NMR) for identity confirmation, to ensure it meets the high standards required for research and industrial use. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, physical characteristics, and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Melting Point	221 - 224 °C
Loss on Drying	≤ 2.0 %
Residue on Ignition	≤ 0.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.