Description

Trifluoroacetaldehyde is a highly versatile fluorinated building block essential for advanced organic synthesis. Its unique reactivity, imparted by the electron-withdrawing trifluoromethyl group, makes it a critical intermediate for introducing the CF3 moiety into complex molecules. This compound is in high demand across the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of trifluoroethylamine derivatives and other active pharmaceutical ingredients (APIs) with enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used to manufacture advanced herbicides, fungicides, and insecticides where the trifluoromethyl group improves efficacy and environmental profile.
• Fluorinated Polymer Production: Serves as a monomer or co-monomer for creating specialty polymers with superior chemical resistance, thermal stability, and low surface energy.
• Organic Synthesis Reagent: Employed in nucleophilic addition reactions, reductive amination, and as a starting material for heterocyclic compounds like trifluoromethyl-substituted pyrimidines and triazoles.
• Liquid Crystal & Electronic Materials: A valuable building block for fluorinated liquid crystals and organic electronic materials used in displays and semiconductors.

Basic Information

Item	Details
Product Name	Trifluoroacetaldehyde
CAS No.	75-90-1
Molecular Formula	C2HF3O
Molecular Weight	98.02 g/mol
Synonyms	Trifluoroethanal; Perfluoroacetaldehyde; 2,2,2-Trifluoroacetaldehyde; Trifluoroacetic Aldehyde; Fluoral; TFA; TFAA; 2,2,2-Trifluoroethanal
EINECS	200-915-7

Quality Control

Our Trifluoroacetaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, NMR, and Karl Fischer titration, to ensure it meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, well-ventilated area. Due to its highly volatile and easily oxidized nature, the container should be kept tightly sealed and away from heat, sparks, and open flames. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.