Description

Chlorotrimethylsilane is a highly versatile and reactive organosilicon compound, serving as a fundamental building block in organosilicon chemistry. Its primary value lies in its ability to act as an efficient silylating and chlorinating agent, introducing the trimethylsilyl (TMS) group to protect reactive functional groups like alcohols and amines. This product is essential for manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used in the synthesis of silicon-based polymers, reagents, and advanced intermediates. Its high volatility and reactivity make it a critical component for precise chemical transformations under controlled conditions.

Application

• Silylating Agent: For the protection of hydroxyl and amino groups in complex organic and pharmaceutical synthesis.
• Silicon Polymer Production: A key monomer and intermediate in the manufacture of silicone fluids, resins, and elastomers.
• Surface Modification: Used to impart hydrophobic properties to glass, silica, and other inorganic materials.
• Laboratory Reagent: Employed as a derivatization agent in analytical chemistry and as a precursor for other organosilicon compounds.
• Agrochemical Synthesis: Intermediate in the production of certain pesticides and herbicides.
• Adhesive & Sealant Formulations: A cross-linking agent and moisture scavenger in silicone-based adhesive systems.

Basic Information

Product Name	Chlorotrimethylsilane
CAS No.	75-77-4
Molecular Formula	C3H9ClSi
Molecular Weight	108.64 g/mol
Synonyms	Trimethylchlorosilane; TMCS; Trimethylsilyl chloride; TMS-Cl; Chlorotrimethylsilicon; Silane, chlorotrimethyl-; NSC 9373; UN 1298
EINECS	200-900-5

Quality Control

Our Chlorotrimethylsilane is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including gas chromatography (GC) for assay and impurity profiling. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support our global B2B clients with the documentation necessary for their regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from heat, sparks, and open flame. Due to its highly volatile and moisture-sensitive nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis and maintain product integrity. Recommended storage temperature is 2-25°C. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.5%
Density (at 20°C)	0.856 - 0.860 g/mL
Refractive Index (n20D)	1.388 - 1.392
Boiling Point	57 - 58 °C
Water Content (Karl Fischer)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.