Description

Borane-Trimethylamine Complex is a versatile and widely used reducing agent in organic synthesis. Its primary value lies in its ability to provide a controlled source of borane (BH₃) for selective reductions, offering advantages in stability and handling over gaseous diborane. This complex is essential for research laboratories and industrial-scale chemical production, particularly in the pharmaceutical and fine chemical sectors for the synthesis of active pharmaceutical ingredients (APIs) and complex organic intermediates.

Application

• Selective Carbonyl Reduction: A key reagent for the chemoselective reduction of aldehydes and ketones to their corresponding alcohols.
• Pharmaceutical Intermediate Synthesis: Used in multi-step synthesis of complex drug molecules, including steroids and other bioactive compounds.
• Hydroboration Reactions: Serves as a convenient source of borane for the hydroboration of alkenes and alkynes, a critical step in creating organoboranes for further functionalization.
• Amino Acid and Peptide Chemistry: Employed for the reduction of carboxylic acids and their derivatives, as well as in the modification of amino acid side chains.
• Polymer Chemistry: Acts as a catalyst or initiator in certain polymerization processes and for the modification of polymer surfaces.
• Fine Chemical Manufacturing: Utilized in the production of specialty chemicals, flavors, and fragrances where precise reduction steps are required.

Basic Information

Product Name	Borane-Trimethylamine Complex
CAS No.	75-22-9
Molecular Formula	C₃H₁₂BN
Molecular Weight	72.95 g/mol
Synonyms	Borane-trimethylamine adduct; Trimethylamine-borane complex; TMAB; Borane-amine complex; N,N,N-Trimethylboranamine; Borazane; TMAB; Me₃N·BH₃
EINECS	200-852-5

Quality Control

Our Borane-Trimethylamine Complex is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as assay, moisture content, and identity confirmation. Our quality management system is designed to meet the stringent requirements of pharmaceutical (GMP) and fine chemical industries, ensuring reliability for your critical synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation and hydrolysis. Keep away from heat, sparks, open flames, and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (Titration)	≥ 97.0%
Melting Point	93 - 96 °C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.