Description

2-Bromo-4-Chloroaniline is a halogenated aniline derivative that serves as a versatile and critical building block in advanced organic synthesis. Its value lies in its ability to introduce both bromine and chlorine substituents onto an aromatic amine core, enabling the creation of complex molecular architectures. This intermediate is essential for manufacturers in the agrochemical and pharmaceutical sectors, where it is used to synthesize active ingredients, dyes, and other high-value specialty chemicals.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of herbicides, fungicides, and pesticides, where its halogenated structure contributes to biological activity.
• Pharmaceutical Synthesis: Employed as a building block for active pharmaceutical ingredients (APIs), particularly in the development of compounds with specific halogenated aromatic motifs.
• Dye and Pigment Manufacturing: Used in the production of azo dyes and other complex colorants, where the amine group facilitates diazotization and coupling reactions.
• Organic Light-Emitting Diodes (OLEDs): Acts as a starting material for electron-transport or host materials in electronic chemicals and advanced materials research.
• Cross-Coupling Reactions: Serves as a substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for creating carbon-nitrogen bonds in fine chemical synthesis.
• Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic pathways and novel compound libraries.

Basic Information

Product Name	2-Bromo-4-Chloroaniline
CAS No.	73-38-1
Molecular Formula	C6H5BrClN
Molecular Weight	206.46 g/mol
Synonyms	4-Chloro-2-bromoaniline; 2-Bromo-4-chlorobenzenamine; 1-Amino-2-bromo-4-chlorobenzene; Benzenamine, 2-bromo-4-chloro-; 2-Bromo-4-chloro-phenylamine; 4-Chloro-2-bromo-phenylamine; (2-Bromo-4-chlorophenyl)amine
EINECS	200-800-7

Quality Control

Our 2-Bromo-4-Chloroaniline is produced under a stringent quality management system to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC, and NMR, to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and specific impurity limits is provided with each shipment, ensuring full traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the material should be handled and stored under conditions that minimize exposure to direct or strong artificial light.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	64 - 68 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.