Description

17A-Ethynyl-1,3,5(10)-Estratriene-3,17B-Diol 3-Methyl Ether is a high-purity synthetic steroid derivative, widely recognized as a key pharmaceutical intermediate. This compound is valued for its precise chemical structure, which is essential for the synthesis of more complex active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical and life sciences sectors for the development and production of steroidal drugs and reference standards.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of steroidal hormones and related therapeutic agents.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control testing of pharmaceutical products.
• Biochemical Research: Serves as a precursor or standard in studies investigating steroid metabolism, receptor binding, and endocrine pathways.
• API Development: Employed in research and development for creating novel steroid-based active pharmaceutical ingredients with targeted therapeutic effects.

Basic Information

Product Name	17A-Ethynyl-1,3,5(10)-Estratriene-3,17B-Diol 3-Methyl Ether
CAS No.	72-33-3
Molecular Formula	C22H28O3
Molecular Weight	340.46 g/mol
Synonyms	Mestranol; Ethynylestradiol 3-Methyl Ether; 17α-Ethynylestradiol 3-Methyl Ether; EE3ME; 3-Methoxy-19-nor-17α-pregna-1,3,5(10)-trien-20-yn-17-ol; 17α-Ethynyl-1,3,5(10)-estratriene-3,17β-diol 3-methyl ether; NSC-71423
EINECS	200-783-8

Quality Control

Our 17A-Ethynyl-1,3,5(10)-Estratriene-3,17B-Diol 3-Methyl Ether is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting standards for pharmaceutical research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.