Description

Ethanone, 2-Chloro-1-(4-Fluoro-3-Methylphenyl)- (9Ci) is a high-purity aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a critical intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its specific halogenated and fluorinated structure enables precise molecular modifications. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce key functional groups into complex molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) and anti-inflammatory agents.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced herbicides and fungicides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Organic Light-Emitting Diode (OLED) Materials: Used in the research and development of electron-transport or host materials for display and lighting technologies.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Advanced Polymer Chemistry: Employed as a monomer or modifier in the synthesis of high-performance polymers with specific thermal or optical properties.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D exploring new reactions, such as cross-coupling and nucleophilic substitution, facilitated by the reactive chloro and carbonyl groups.

Basic Information

Product Name	Ethanone, 2-Chloro-1-(4-Fluoro-3-Methylphenyl)- (9Ci)
CAS No.	696616-24-7
Molecular Formula	C9H8ClFO
Molecular Weight	186.61 g/mol
Synonyms	2-Chloro-1-(4-fluoro-3-methylphenyl)ethanone; 1-(4-Fluoro-3-methylphenyl)-2-chloroethanone; 2-Chloro-4'-fluoro-3'-methylacetophenone; 4'-Fluoro-3'-methyl-2-chloroacetophenone; 2-Chloro-1-(4-fluoro-3-methylphenyl)ethan-1-one; α-Chloro-4-fluoro-3-methylacetophenone
EINECS	Contact for details

Quality Control

Our Ethanone, 2-Chloro-1-(4-Fluoro-3-Methylphenyl)- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.